It was not possible to conduct a study of its kind as it was difficult for the living cells of the film in detail over a long period without exposing the cells to fluorescent light nuisance. Alternatively, researchers in this study used digital holographic microscopy, a technique in which cells are exposed to laser light for only short periods of time very limited.The results of the research group through new and important knowledge about how these can cause chromosomal damage. Filming cancer cells as they grow over a long period of time, they found that cancer cells can undergo a special form of division. Normal cells divide in two opposite directions and we already know that cancer cells sometimes divided into three areas.
“At the moment, the most important thing is to wait for our results are confirmed by other studies,” said David Gisselsson North.
Filming cancer cells as they grow, the researchers found that cancer cells can undergo a special form of division is not seen in healthy cells.
Further progress has been made in understanding the origins of genetic changes in cancer cells. The prevailing theory was that the genetic changes in cancer cells occur in stages over a long period. However, a recent study by researchers at Lund University shows that this should not be nearly so, but rather that the cells can be subjected to different chromosomal changes at the same time.
The results are presented in the scientific journal PNAS. The basis of this study is a researcher and physician David Gisselsson North and his colleagues as a research group.
“Now we can easily understand why this is so, because it is believed that the accumulation of cells with genes from each other within a tumor, respond less well to chemotherapy. But this is still a theory,” says David Gisselsson North.
The hope is that this type of cell division can be used in any way as a target for the treatment of cancer, but research is complicated and much work remains to be done.
Both the research team at Lund and others have shown that a high percentage of abnormal cell divisions of the sort that have now studied are associated with an increased risk of children with Wilms ‘tumor’ died of disease.
“These large chromosomal changes at once may explain why tumors in young children, who have not had much time to grow, can show extreme variation in genetic makeup,” he said.